Test Detail

Liver-Kidney Microsome (LKM-1) TYPE-1

Liver-Kidney Microsome type-1 (LKM-1) refers to antibodies targeting the cytochrome P450 2D6 (CYP2D6) enzyme, primarily found in liver and kidney cells. These autoantibodies are a key diagnostic marker for Type 2 Autoimmune Hepatitis (AIH), particularly in young women. While LKM-1 antibodies are a hallmark of this chronic, inflammatory liver disease, they can also sometimes appear in other conditions like Hepatitis C infection, so testing requires context with other autoantibodies